Question:

What modifiers are required for claims submitted for ESAs administered to non-ESRD patients (J0881 and J0885)?

Answer:

According to the Centers for Medicare & Medicaid Services (CMS), all non-ESRD claims billing HCPCS level II code J0881 (Injection, darbepoetin alfa, 1 microgram [non-ESRD use]) and J0885 (injection, epoetin alfa, [for non-ESRD use], 1000 units) must report one of the following modifiers:

  • EA: ESA, anemia, chemo-induced
  • EB: ESA, anemia, radio-induced
  • EC: ESA, anemia, non-chemo/radio

Institutional claims that do not report one of the above modifiers will be returned to the provider.

Professional claims that are billed without the required modifiers will be returned as unprocessable.

The above information can be found in the Medicare Claims Processing Manual, Chapter 17, section 80.9.

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