Question:

When is CPT® add-on code +0993T reported for augmentative software analysis performed with a CT scan of the heart? Case Example: A patient with multiple cardiovascular risk factors, including obesity, hypertension, a history of smoking, and elevated inflammatory markers, underwent coronary CT angiography (CCTA) for evaluation of coronary artery disease. The patient was placed supine in the CT scanner, and a gated coronary CT angiography study was performed using standard institutional protocol with intravenous contrast. Image quality was confirmed to be adequate for diagnostic review. Immediately following image acquisition, the CCTA dataset was transferred to an AI-powered perivascular fat analysis platform. The software automatically identified the coronary arteries, extracted perivascular fat regions, and calculated vessel-specific fat attenuation index (FAI) measurements associated with coronary vascular inflammation. Clinical risk factors, including body mass index (BMI), smoking history, high-sensitivity C-reactive protein (hs-CRP), and blood pressure, were incorporated into the software analysis to refine the inflammation-based risk assessment. The platform generated a comprehensive cardiac inflammation profile that integrated coronary plaque characteristics with biologic inflammatory markers. The interpreting cardiologist reviewed both the primary CCTA findings and the AI-generated FAI metrics. The combined report concluded: (1) no obstructive coronary artery disease, (2) mixed noncalcified plaque within the proximal left anterior descending (LAD) artery, and (3) elevated FAI values indicating increased vascular inflammatory activity. Based on these findings, therapy intensification was recommended.

Answer:

This case illustrates appropriate reporting of CPT® add-on code +0993T. The augmentative software analysis was performed in conjunction with a same-session CT scan of the heart, specifically a coronary CT angiography (CCTA). Following image acquisition, the CT dataset was analyzed by software that evaluated perivascular fat attenuation and incorporated patient-specific clinical data to generate additional information regarding coronary inflammation and cardiovascular risk. The interpreting physician reviewed these augmentative findings together with the primary CCTA results to support clinical decision-making. The software analysis provided information beyond the anatomical assessment of the coronary arteries alone by integrating imaging findings with biologic markers associated with vascular inflammation. Because the augmentative analysis was performed on a cardiac CT study obtained during the same encounter, reporting +0993T is appropriate.

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