Master the upcoming ICD-10 code and IPPS changes! Prepare your team for the upcoming changes taking effect on October 1. Discover the benefits of IPPSPalooza and how it can drive your success. Click here >

Look What’s New in the New Codes: MINOCA and INOCA

EDITOR’S NOTE: The acronyms MINOCA (myocardial infarction with non-obstructive coronary arteries) and INOCA (ischemia and no obstructive coronary artery disease) recently have come into use in the healthcare industry. ICD10monitor publisher Chuck Buck caught up to and addressed this topic with board-certified cardiologist Stephen Sokolyk, a graduate of University of Texas Southwestern Medical School in Dallas who holds a master’s degree in healthcare administration from Trinity University in San Antonio and has practiced invasive/non-interventional cardiology for 19 years. For the past three years, he has been a physician advisor for care transitions management and utilization management with Texas Health Resources (THR) in Arlington, Texas. Excerpts from that interview follow.

Among the new 2018 ICD-10-CM codes are the ones for heart failure classifications and myocardial infarction (MI) types. We understand that the heart failure classification is not the New York Hospital Association classifications, but those introduced by the American College of Cardiology (ACC) and the American Heart Association (AHA).

The proposed new MI codes include one for unspecified MI, one for type 2 MI (supply-demand mismatch), and one to encompass procedure-related MI and MI resulting in sudden death (types 3-5).

For heart failure, there are several new codes for isolated right-sided failure that address a definite gap in the codes. There are also new codes for right heart failure due to left heart failure, biventricular failure, high-output failure (e.g. from anemia, dialysis shunt, or thyrotoxicosis), and end-stage heart failure. The latter code also includes the term “stage D heart failure,” which is indeed the final stage in the ACC/AHA scheme. All the new heart failure codes serve to align coding with contemporary documentation of heart failure, as encouraged by ACC and AHA.

And now there is the expectation of a 2017 update of the 2012 Third Universal Definition of myocardial infarction. Could you provide some background on this?

The Third Universal Definition of MI was a cooperative venture among the ACC, AHA, European Society of Cardiology, and World Heart Federation, and it was published in 2012.  The impetus for the updated definitions was the widespread introduction of very sensitive biomarkers (troponin I and T) and sensitive imaging techniques (especially cardiac MRI), which seemed to identify very small amounts of myocardial injury in situations in which it had not previously been suspected.

The definition of an MI was a rise and fall in troponin, with at least one reading above the 99th percentile for the population, accompanied by a strong pre-test likelihood.

The classic MI due to plaque rupture in a coronary artery was designated as a type 1 infarction. Note that the 2012 article mentions that 5-20 percent of patients will have mild or no CAD at angiography. Myocardial necrosis due to oxygen supply/demand mismatch is type 2 MI; this category includes vasospastic MI. Sudden death with evidence of acute MI but no biomarkers is type 3 MI. Cardiac necrosis associated with percutaneous coronary intervention (4a) and stent thrombosis (4b) is type 4 MI. Cardiac necrosis associated with CABG is type 5 MI.

These definitions have been updated about once every five years, so a revision this year would be timely.  Presumably, new definitions will separate out at least some MINOCA.

What is the origin of these new terms: myocardial infarction with non-obstructive coronary arteries (MINOCA) and ischemia and no obstructive coronary artery disease (INOCA)?

It has been common for cardiologists (myself included) to describe patients with chest pain and abnormal stress tests, but mild or no CAD on catheterization, as “false positives.” However, studies have long shown that such patients have a worse prognosis than patients with normal stress tests. In recognition of this fact, these patients have now been designated as “INOCA.”

MINOCA patients have been particularly common with the advent of sensitive troponin testing. For the most part, cardiologists have done reasonably well in identifying the causes of the troponin elevations, though many cases have remained troubling, and some have still been written off as false positives. The term itself was coined in 2013. It often applies to type 2 MI.

What are the causes of MINOCA and INOCA?

Generally speaking, INOCA is associated with conventional cardiac risk factors such as hypertension, hyperlipidemia, and obesity. It is much more common in women. Underlying mechanisms may involve decreased coronary flow reserve and elevated platelet reactivity. Coronary intravascular ultrasound can reveal more extensive atherosclerosis than is appreciated on angiography, due to positive remodeling. This may indicate a diffuse inflammatory state in the vessels.

MINOCA encompasses a heterogeneous group of issues, including:

  1. Plaque rupture without severe obstruction, but with resultant vasospasm, microscopic thromboembolism, or thrombosis with spontaneous thrombolysis. Technically a type 1 MI
  2. Vasospasm without plaque rupture
  3. Thromboembolism due to thrombophilic state
  4. Coronary dissection, if not visible on angiography
  5. Takotsubo (stress) cardiomyopathy
  6. Type 2 MI with other primary diagnosis (e.g. sepsis, hypertensive crisis, arrhythmia, severe valvular disease)

Pulmonary embolism and myocarditis can cause this picture, but are not considered to produce myocardial infarction.

In this context, what do coders and clinical documentation integrity specialists need to know about MINOCA and INOCA – and when?

These diagnoses only come into consideration after cardiac catheterization (and perhaps infrequently after coronary CT) since they require objective evidence of non-obstructive CAD. Thus, catheterizations that do not result in percutaneous intervention or CABG should be scrutinized. We need to be sure that the physician documents the best possible explanation for the findings of positive troponins and non-obstructive CAD, rather than documenting “negative cath” and leaving it at that. Newly prescribed medications can be a clue. For example, calcium-channel blockers might indicate vasospasm as a suspected mechanism of MINOCA. 

“Negative cath” as the last word is especially likely in the context of ischemia without elevated troponins. Coders and CDI specialists should be looking for INOCA in those patients.

PROGRAM NOTE: Dr. Sokolyk will be the special guest on today’s edition of Talk Ten Tuesdays at 10 a.m. EST.

Print Friendly, PDF & Email

Chuck Buck

Chuck Buck is the publisher of RACmonitor and is the program host and executive producer of Monitor Monday.

Related Stories

Leave a Reply

Please log in to your account to comment on this article.

Featured Webcasts

Mastering the Two-Midnight Rule: Keys to Navigating Short-Stay Admissions with Confidence

Mastering the Two-Midnight Rule: Keys to Navigating Short-Stay Admissions with Confidence

The CMS Two-Midnight Rule and short-stay audits are here to stay, impacting inpatient and outpatient admissions, ASC procedures, and Medicare Parts C & D. New for 2024, the Two-Midnight Rule applies to Medicare Advantage patients, requiring differentiation between Medicare plans affecting Case Managers, Utilization Review, and operational processes and knowledge of a vital distinction between these patients that influences post-discharge medical reviews and compliance risk. Join Michael G. Calahan for a comprehensive webcast covering federal laws for all admission processes. Gain the knowledge needed to navigate audits effectively and optimize patient access points, personnel, and compliance strategies. Learn Two-Midnight Rule essentials, Medicare Advantage implications, and compliance best practices. Discover operational insights for short-stay admissions, outpatient observation, and the ever-changing Inpatient-Only Listing.

Print Friendly, PDF & Email
September 19, 2023
Secondary Diagnosis Coding: A Deep Dive into Guidelines and Best Practices

Secondary Diagnosis Coding: A Deep Dive into Guidelines and Best Practices

Explore comprehensive guidelines and best practices for secondary diagnosis coding in our illuminating webcast. Delve into the intricacies of accurately assigning secondary diagnosis codes to ensure precise medical documentation. Learn how to navigate complex scenarios and adhere to coding regulations while enhancing coding proficiency. Our expert-led webcast covers essential insights, including documentation requirements, sequencing strategies, and industry updates. Elevate your coding skills and stay current with the latest coding advancements so you can determine the correct DRG assignment to optimize reimbursement, support medical decision-making, and maintain compliance.

Print Friendly, PDF & Email
September 20, 2023
Principal Diagnosis Coding: Mastering Selection and Sequencing

Principal Diagnosis Coding: Mastering Selection and Sequencing

Enhance your inpatient coding precision and revenue with Principal Diagnosis Coding: Mastering Selection and Sequencing. Join our expert-led webcast to conquer the challenges of principal diagnosis selection and sequencing. We’ll decode the intricacies of ICD-10-CM guidelines, equipping you with a clear grasp of the rules and the official UHDDS principal diagnosis definition. Uncover the crucial role of coding conventions, master the sequencing of related conditions, and confidently tackle cases with equally valid principal diagnoses.

Print Friendly, PDF & Email
September 14, 2023
2024 IPPS Summit: Final Rule Update with Expert Insights and Analysis

2024 IPPS Summit: Final Rule Update with Expert Insights and Analysis

Only ICD10monitor delivers what you need: updates on must-know changes associated with the FY24 Inpatient Prospective Payment System (IPPS) Final Rule, including new ICD-10-CM/PCS codes, plus insights, analysis and answers to questions from the country’s most respected subject matter experts.

Print Friendly, PDF & Email
2024 IPPS Summit Day 3: MS-DRG Shifts and NTAPs

2024 IPPS Summit Day 3: MS-DRG Shifts and NTAPs

This third session in our 2024 IPPS Summit will feature a review of FY24 changes to the MS-DRG methodology and new technology add-on payments (NTAPs), presented by senior healthcare consultant Laurie Johnson, with bonus insights and analysis from two acclaimed subject matter experts

Print Friendly, PDF & Email
August 17, 2023

Trending News