CMS Releases New ICD-10-PCS Codes for COVID-19

New procedure codes do not impact the MS-DRG assignment.

The Centers for Medicare and Medicaid Services (CMS) released 21 new ICD-10-PCS codes that apply to the vaccination or treatment of COVID-19. These codes are effective January 1, 2021.

The procedure codes introduce six specific medications that can be used for treatment of COVID-19. The drugs are leronlimab, etesevimab, bamlanivimab, REGN-COV2, CD24Fc immunomodulator, and baricitinib. In addition, an entry for other new technology monoclonal antibody has been added. The approaches vary for the medications so it will be important to review the ICD-10-PCS tables.

Leronlimab is a monoclonal antibody used to treat HIV. This medication is currently in clinical trials for treatment of COVID. The drug protects health T-cells from viral infection. Etesevimab is a recombinant fully human monoclonal neutralizing antibody which binds specifically to the SARS-CoV2 surface spike protein receptor binding domain.  Bamlanivimab is a neutralizing immunoglobulin G1 (IgG1) monoclonal antibody which targets the spike protein of SARS-CoV2. It neutralizes the virus by blocking viral attachment and entry into human cells.  REGN-COV2 is an antiviral antibody cocktail which has been tested on rhesus macaques and golden hamsters.   CD24Fc (SACCOVID) immunomodulator is a fusion protein which reduces the incidence of viral pneumonia and promotes faster recovery.   Baricitinib is a drug that has been approved by the Food and Drug Administration (FDA) for treatment of COVID-19 in combination with remdesivir. This drug combination is used to treat patients who require supplemental oxygen, invasive mechanical ventilation, or extracorporeal membrane oxygenation (ECMO).   This drug blocks the activity of one or more of a specific family of enzymes and interferes with the pathway to inflammation.

The new codes also include vaccination for COVID-19. The vaccines may require one or two doses of the vaccine. The options include subcutaneous or muscles with a percutaneous approach.  These codes do not have the proprietary name of the vaccine included.   The new ICD-10-PCS codes are used in conjunction with these CPT® codes:

Payment Allowances and Effective Dates for COVID-19 Vaccines and their Administration during the Public Health Emergency:

 Johnson120720 1
Johnson120720 1

Payment Allowances and Effective Dates for COVID-19 Monoclonal Antibodies and their Administration during the Public Health Emergency:

Johnson120720 1

Here is the listing of the new ICD-10-PCS codes per the CMS announcement:

Johnson120720 1
Johnson120720 1
Johnson120720 1

The first decision that should be made is if the inpatient coders will assign these codes. The information can be captured from the detail charges. It is important to review the medications and identify which drugs are used by your facility. Identify the documentation in the electronic health record and communicate this information to the coders.   This information can be added to your facility specific guidelines to promote consistent data capture.    If you code the vaccination procedures, then the Z23 diagnosis code should be assigned too.

On another note, the Centers for Disease Control and Prevention (CDC) officially listed the new ICD-10-CM diagnosis codes for COVID on December 3, 2020. The addenda have been posted on the CDC website and can be found under Resources.    There are six new diagnosis codes that are effective January 1, 2021.

The release of new diagnosis and procedure codes has added more activity to all already busy season.  Happy Holidays!

Programming Note: Laurie Johnson is a member of the ICD10monitor editorial board and a permanent panelist on Talk Ten Tuesdays. Listen to her live reporting today and every Tuesday on Talk Ten Tuesdays, 10 a.m. EST.

Resources:

https://www.cms.gov/Medicare/Medicare-Fee-for-Service-Payment/AcuteInpatientPPS/MS-DRG-Classifications-and-Software

https://www.cms.gov/medicare/icd-10/2021-icd-10-pcs

https://www.cdc.gov/nchs/data/icd/Announcement-New-ICD-code-for-coronavirus-19-508.pdf

https://www.cms.gov/medicare/medicare-part-b-drug-average-sales-price/covid-19-vaccines-and-monoclonal-antibodies

https://www.cdc.gov/nchs/icd/icd10cm.htm

Facebook
Twitter
LinkedIn

Laurie M. Johnson, MS, RHIA, FAHIMA, AHIMA Approved ICD-10-CM/PCS Trainer

Laurie Johnson is currently a senior healthcare consultant for Revenue Cycle Solutions, based in Pittsburgh, Pa. Laurie is an AHIMA-approved ICD-10-CM/PCS trainer. She has more than 35 years of experience in health information management and specializes in coding and related functions. She has been a featured speaker in over 40 conferences. Laurie is a member of the ICD10monitor editorial board and is a permanent panelist on Talk Ten Tuesdays

Related Stories

New Online Drug Lookup Tool Unveiled

New Online Drug Lookup Tool Unveiled

MedLearn Media is launching an online resource believed to be useful for professional coders, charge capture, compliance, and revenue integrity specialists alike. DrugCode Pro is

Read More

Leave a Reply

Please log in to your account to comment on this article.

Featured Webcasts

The Cost of Ignoring Risk Adjustment: How HCCs Impact Revenue & Compliance

The Cost of Ignoring Risk Adjustment: How HCCs Impact Revenue & Compliance

Stop revenue leakage and boost hospital performance by mastering risk adjustment and HCCs. This essential webcast with expert Cheryl Ericson, RN, MS, CCDS, CDIP, will reveal how inaccurate patient acuity documentation leads to lost reimbursements through penalties from poor quality scores. Learn the critical differences between HCCs and traditional CCs/MCCs, adapt your CDI workflows, and ensure accurate payments in Medicare Advantage and value-based care models. Perfect for HIM leaders, coders, and CDI professionals.  Don’t miss this chance to protect your hospital’s revenue and reputation!

May 29, 2025
I050825

Mastering ICD-10-CM Coding for Diabetes and it’s Complications: Avoiding Denials & Ensuring Compliance

Struggling with ICD-10-CM coding for diabetes and complications? This expert-led webcast clarifies complex combination codes, documentation gaps, and sequencing rules to reduce denials and ensure compliance. Dr. Angela Comfort will provide actionable strategies to accurately link diabetes to complications, improve provider documentation, and optimize reimbursement—helping coders, CDI specialists, and HIM leaders minimize audit risks and strengthen revenue integrity. Don’t miss this chance to master diabetes coding with real-world case studies, key takeaways, and live Q&A!

May 8, 2025
2025 Coding Clinic Webcast Series

2025 ICD-10-CM/PCS Coding Clinic Update Webcast Series

Uncover critical guidance. HIM coding expert, Kay Piper, RHIA, CDIP, CCS, provides an interactive review on important information in each of the AHA’s 2025 ICD-10-CM/PCS Quarterly Coding Clinics in easy-to-access on-demand webcasts, available shortly after each official publication.

April 14, 2025

Trending News

Featured Webcasts

Medicare Advantage 2026: Navigating New Rules, Denial Protections & SDoH Shifts

Medicare Advantage 2026: Navigating New Rules, Denial Protections & SDoH Shifts

Stay ahead of Medicare Advantage’s 2025-2026 regulatory changes in this critical webcast featuring expert Tiffany Ferguson, LMSW, CMAC, ACM. Learn how new CMS rules limit MA plan denials, protect hospitals from retroactive claim reopenings, and modify Two-Midnight Rule enforcement—plus key insights on omitted SDoH mandates and heightened readmission scrutiny. Discover actionable strategies to safeguard revenue, ensure compliance, and adapt to evolving health equity priorities before the June 2025 deadline. Essential for hospitals, revenue cycle teams, and compliance professionals navigating MA’s shifting landscape.

May 28, 2025
Navigating the 3-Day & 1-Day Payment Window: Compliance, Billing, and Revenue Protection

Navigating the 3-Day & 1-Day Payment Window: Compliance, Billing, and Revenue Protection

Struggling with CMS’s 3-Day Payment Window? Join compliance expert Michael G. Calahan, PA, MBA, CCO, to master billing restrictions for pre-admission and inter-facility services. Learn how to avoid audit risks, optimize revenue cycle workflows, and ensure compliance across departments. Critical for C-suite leaders, providers, coders, revenue cycle teams, and compliance teams—this webcast delivers actionable strategies to protect reimbursements and meet federal regulations.

May 15, 2025
Audit-Proof Your Wound Care Procedures: Expert Insights on Compliance and Risk Mitigation

Audit-Proof Your Wound Care Procedures: Expert Insights on Compliance and Risk Mitigation

Providers face increasing Medicare audits when using skin substitute grafts, leaving many unprepared for claim denials and financial liabilities. Join veteran healthcare attorney Andrew B. Wachler, Esq., in this essential webcast and master the Medicare audit process, learn best practices for compliant billing and documentation, and mitigate fraud and abuse risks. With actionable insights and a live Q&A session, you’ll gain the tools to defend your practice and ensure compliance in this rapidly evolving landscape.

April 17, 2025
Utilization Review Essentials: What Every Professional Needs to Know About Medicare

Utilization Review Essentials: What Every Professional Needs to Know About Medicare

Dr. Ronald Hirsch dives into the basics of Medicare for clinicians to be successful as utilization review professionals. He’ll break down what Medicare does and doesn’t pay for, what services it provides and how hospitals get paid for providing those services – including both inpatient and outpatient. Learn how claims are prepared and how much patients must pay for their care. By attending our webcast, you will gain a new understanding of these issues and be better equipped to talk to patients, to their medical staff, and to their administrative team.

March 20, 2025

Trending News

Prepare for the 2025 CMS IPPS Final Rule with ICD10monitor’s IPPSPalooza! Click HERE to learn more

Get 15% OFF on all educational webcasts at ICD10monitor with code JULYFOURTH24 until July 4, 2024—start learning today!

CYBER WEEK IS HERE! Don’t miss your chance to get 20% off now until Dec. 2 with code CYBER24Â