Breaking Through Breast Ultrasound and Opto-Acoustic Imaging Codes to Achieve Success in 2025 Featuring an Exclusive Offer

Breaking Through Breast Ultrasound and Opto-Acoustic Imaging Codes to Achieve Success in 2025 Featuring an Exclusive Offer

May is Women’s Health Month—a powerful reminder of the importance of prioritizing preventive care, especially when it comes to breast health. Mammography and breast-related coding remain among the most effective tools for the early detection of breast cancer, often identifying issues before symptoms arise and leading to better outcomes. Imaging scans also play an integral role in treatment programs following a diagnosis. This month, we explore the nuances of ultrasound breast scans and opto-acoustic imaging, along with professional tips and an exclusive offer to help you succeed.

Unlocking Ultrasound Breast Scan and Opto-Acoustic Imaging Codes

76641 Ultrasound, breast, unilateral, real time with image documentation, including axilla when performed; complete
76642 Ultrasound, breast, unilateral, real time with image documentation, including axilla when performed; limited
+0857T Opto-acoustic imaging, breast, unilateral, including axilla when performed, real-time with image documentation, augmentative analysis and report (List separately in addition to code for primary procedure)

If you’ve been coding breast ultrasound services for a while, you may remember when CPT code 76645 was retired back in 2015. To replace these codes, two new codes 76641 and 76642 were created to give more specified options for reporting—both designed to report unilateral breast ultrasound services.

Here’s the quick breakdown:
  • 76641 is for a complete exam, meaning all four quadrants of the breast and the retroareolar region must be evaluated.
  • 76642 is for a limited study—basically, anything less than complete.

Both codes include imaging of the axilla when medically necessary, and you’ll often see them used alongside mammography.

Fast forward to 2023—add-on code +0857T has now entered the picture. This new Category III code was introduced for opto-acoustic (OA) imaging—a hybrid technique combining laser light and ultrasound to visualize breast masses. What was the reasoning for entering a new code? Better identification of benign pathology and, ideally, fewer unnecessary biopsies. Code +0857T is used in addition to 76641 or 76642 and active still in 2025.

Top Expert  Billing Tips for Success in 2025
  1. Automated whole breast ultrasound (ABUS), for secondary screening for women with dense breasts, is reported with the regular breast ultrasound codes 76641 or 76642. This should be a screening exam, so a screening diagnosis code should be reported. However, it is important to note that ABUS is not a substitute for a screening mammogram. Note that some payers may consider ABUS investigational, and therefore, non-covered.
  2. For screening ultrasound of the breast, report 76641 or 76642 and the appropriate ICD-10-CM screening diagnosis code as applicable. In addition, it is recommended that a secondary diagnosis be reported to communicate to the payer that the study was performed on a high-risk patient. Coverage will be subject to payer guidelines.
  3. For ultrasounds performed bilaterally, report with modifiers LT and RT or 50, or with a quantity of 2, as per payer guidelines.
  4. Typically, modifiers are not required for add-on CPT codes (such as 0857T), unless an NCCI edit is generated. If, however, your specific payer requires one, and depending upon whether you are billing for hospital (Part A) or physician (Part B) services, the following modifiers may be required: LT, RT, 50, 59 (or one of the X{EPSU} modifiers) or 76. Guidelines in the CPT manual now state that modifier 50 may not be reported with add-on codes. However, local payer policy may differ. Be sure to clarify reporting requirements for your specific region.
  5. While the physician can document either by quadrant or by clock position, ICD-10-CM diagnosis codes require quadrant. Refer also to the SEER Diagram in Appendix F.
  6. Report with revenue code 0402.
  7. Assign modifier 26 to describe the professional component when technical services provided are hospital-based.
⚠️ Don’t Miss Out! An Exclusive Insider Offer for You:

These are not all the tips and knowledge necessary for mammography success. Now through May 30, get 30% off the Breast and Bone Density Procedure Coding Guide using code WOMENSHEALTH25.

This expert resource is packed with:
✔ 2025 CPT code updates and explanations
✔ Billing tips and guidance for tricky procedures
✔ Insight into dense breast notification laws
✔ COVID-19 coding clarification

Stay compliant, protect reimbursement, and code with confidence—all while supporting better outcomes in women’s health.

Facebook
Twitter
LinkedIn

Bryan Nordley

Bryan Nordley is a seasoned professional writer, strategist, and researcher with over a decade’s worth of combined experience. Bryan launched his professional health writing career at the University of British Columbia’s Faculty of Medicine, one of the top 30 faculty of medicine programs in the world, working under the School of Public Health as a communications assistant. From there, he expanded his expertise and knowledge into private healthcare and podiatry before taking the role of healthcare writer at MedLearn Media. Bryan is the lead writer for the MedLearn Publishing brand previously producing both the acclaimed radiology and laboratory compliance manager newsletter products, while currently writing the compliance questions of the week which reach over 10,000 subscribers, creating the MedLearn Publishing Insights blogs and collaborating with operations and nationally renowned subject matter experts, in addition to serving as an editor for a variety of MedLearn publications along with marketing initiatives. Bryan continues to keep his pulse on the latest healthcare industry news, analyzing and reporting with strategic insight.

Related Stories

Leave a Reply

Please log in to your account to comment on this article.

Featured Webcasts

Sepsis Sequencing in Focus: From Documentation to Defensible Coding

Sepsis sequencing continues to challenge even experienced coding and CDI professionals, with evolving guidelines, documentation gaps, and payer scrutiny driving denials and data inconsistencies. In this webcast, Payal Sinha, MBA, RHIA, CCDS, CDIP, CCS, CCS-P, CCDS-O, CRC, CRCR, provides clear guideline-based strategies to accurately code sepsis, severe sepsis, and septic shock, assign POA indicators, clarify the relationship between infection and organ dysfunction, and align documentation across teams. Attendees will gain practical tools to strengthen audit defensibility, improve first-pass accuracy, support appeal success, reduce denials, and ensure accurate quality reporting, empowering organizations to achieve consistent, compliant sepsis coding outcomes.

March 26, 2026
I022426_SQUARE

Fracture Care Coding: Reduce Denials Through Accurate Coding, Sequencing, and Modifier Use

Expert presenters Kathy Pride, RHIT, CPC, CCS-P, CPMA, and Brandi Russell, RHIA, CCS, COC, CPMA, break down complex fracture care coding rules, walk through correct modifier application (-25, -57, 54, 55), and clarify sequencing for initial and subsequent encounters. Attendees will gain the practical knowledge needed to submit clean claims, ensure compliance, and stay one step ahead of payer audits in 2026.

February 24, 2026
Mastering Principal Diagnosis: Coding Precision, Medical Necessity, and Quality Impact

Mastering Principal Diagnosis: Coding Precision, Medical Necessity, and Quality Impact

Accurately determining the principal diagnosis is critical for compliant billing, appropriate reimbursement, and valid quality reporting — yet it remains one of the most subjective and error-prone areas in inpatient coding. In this expert-led session, Cheryl Ericson, RN, MS, CCDS, CDIP, demystifies the complexities of principal diagnosis assignment, bridging the gap between coding rules and clinical reality. Learn how to strengthen your organization’s coding accuracy, reduce denials, and ensure your documentation supports true medical necessity.

December 3, 2025

Proactive Denial Management: Data-Driven Strategies to Prevent Revenue Loss

Denials continue to delay reimbursement, increase administrative burden, and threaten financial stability across healthcare organizations. This essential webcast tackles the root causes—rising payer scrutiny, fragmented workflows, inconsistent documentation, and underused analytics—and offers proven, data-driven strategies to prevent and overturn denials. Attendees will gain practical tools to strengthen documentation and coding accuracy, engage clinicians effectively, and leverage predictive analytics and AI to identify risks before they impact revenue. Through real-world case examples and actionable guidance, this session empowers coding, CDI, and revenue cycle professionals to shift from reactive appeals to proactive denial prevention and revenue protection.

November 25, 2025

Trending News

Featured Webcasts

Compliance for the Inpatient Psychiatric Facility (IPF-PPS): Minimizing Federal Audit Findings by Strengthening Best Practices

Federal auditors are intensifying their focus on inpatient psychiatric facilities, using advanced data analytics to spotlight outliers and pursue high‑dollar repayments. In this high‑impact webcast, Michael Calahan, PA, MBA, Compliance Officer and V.P., Hospital & Physician Compliance, breaks down what regulators are really targeting in IPF-PPS admissions, documentation, treatment and discharge planning. Attendees will learn practical steps to tighten processes, avoid common audit triggers and protect reimbursement and reduce the risk of multimillion-dollar repayment demands.

April 9, 2026

Mastering MDM for Accurate Professional Fee Coding

In this timely session, Stacey Shillito, CDIP, CPMA, CCS, CCS-P, CPEDC, COPC, breaks down the complexities of Medical Decision Making (MDM) documentation so providers can confidently capture the true complexity of their care. Attendees will learn practical, efficient strategies to ensure documentation aligns with current E/M guidelines, supports accurate coding, and reduces audit risk, all without adding to charting time.

March 31, 2026

The PEPPER Returns – Risk and Opportunity at Your Fingertips

Join Ronald Hirsch, MD, FACP, CHCQM for The PEPPER Returns – Risk and Opportunity at Your Fingertips, a practical webcast that demystifies the PEPPER and shows you how to turn complex claims data into actionable insights. Dr. Hirsch will explain how to interpret key measures, identify compliance risks, uncover missed revenue opportunities, and understand new updates in the PEPPER, all to help your organization stay ahead of audits and use this powerful data proactively.

March 19, 2026

Top 10 Audit Targets for 2026-2027 for Hospitals & Physicians: Protect Your Revenue

Stay ahead of the 2026-2027 audit surge with “Top 10 Audit Targets for 2026-2027 for Hospitals & Physicians: Protect Your Revenue,” a high-impact webcast led by Michael Calahan, PA, MBA. This concise session gives hospitals and physicians clear insight into the most likely federal audit targets, such as E/M services, split/shared and critical care, observation and admissions, device credits, and Two-Midnight Rule changes, and shows how to tighten documentation, coding, and internal processes to reduce denials, recoupments, and penalties. Attendees walk away with practical best practices to protect revenue, strengthen compliance, and better prepare their teams for inevitable audits.

January 29, 2026

Trending News

CYBER WEEK IS HERE! Don’t miss your chance to get 20% off now until Dec. 1 with code CYBER25

CYBER WEEK IS HERE! Don’t miss your chance to get 20% off now until Dec. 2 with code CYBER24